ダニ（Df）抽出物（免疫用）
| コード | 包装 | 価格 |
|---|---|---|
| 10108 | 1 mL | ¥40,000 |
- 抗原
- コナヒョウヒダニ（別称：House dust mite）
Dermatophagoides farinae - 原料
- コナヒョウヒダニ
- 規格
- ・総蛋白量 1 mg/vial 含有（BSAを標準液にしたLowry法で測定）
・0.22 μmフィルター滅菌済
・アジュバント、防腐剤は未添加 - 成分
- コナヒョウヒダニアレルゲンを含む抽出物、PBS溶液
- 保存
- -20 ℃以下
くり返しの凍結融解は避けてください。 - 注意
- 本品は研究用試薬です。ヒトへの使用はできません。
本品にはアレルゲン性があります。お取り扱いの際には、白衣、ゴーグル、マスク、グローブなどを装着して下さい。
モデルマウス作製の使用例
BALB/c、C57BL/6に本製品を経鼻投与することで、喘息の病変を誘導できます（アジュバント不要）。
参考文献
Crucial role of stimulator of interferon genes-dependent signaling in house dust mite extract-induced IgE production. Sci. Rep. 11, 13157 (2021). [Pubmed, Full text]
Acute and subacute oral toxicity of deoxynivalenol exposure in a Dermatophagoides farinae induced murine asthma model. Toxicol. Sci. kfaa168, (2020). [Pubmed, Full text]
TLR9–IL-2 axis exacerbates allergic asthma by preventing IL-17A hyperproduction. Sci. Rep. 10, 1–17 (2020).[Pubmed, Full text]
The Nonantibiotic Macrolide EM900 Attenuates House Dust Mite-Induced Airway Inflammation in a Mouse Model of Obesity-Associated Asthma. Int. Arch. Allergy Immunol. (2020). [Pubmed, Full text]
The non-antibiotic macrolide EM900 attenuates HDM and poly(I:C)-induced airway inflammation with inhibition of macrophages in a mouse model. Inflamm. Res. 69, 139–151 (2020). [Pubmed, Full text]
Activation of aryl hydrocarbon receptor by benzo[a]pyrene increases interleukin 33 expression and eosinophil infiltration in a mouse model of allergic airway inflammation. J. Appl. Toxicol. (2020). [Pubmed, Full text]
Time-dependent distinct roles of Toll-like receptor 4 in a house dust mite-induced asthma mouse model. Scand. J. Immunol. 87, (2018). [Pubmed, Full text]
Saturated Fatty Acid Increases Lung Macrophages and Augments House Dust Mite-Induced Airway Inflammation in Mice Fed with High-Fat Diet. Inflammation 40, 1072–1086 (2017). [Pubmed, Full text]
Interleukin-33 from Monocytes Recruited to the Lung Contributes to House Dust Mite-Induced Airway Inflammation in a Mouse Model. PLoS One 11, e0157571 (2016). [Pubmed, Full text]
IL-10-producing lung interstitial macrophages prevent neutrophilic asthma. Int. Immunol. 28, 489–501 (2016). [Pubmed, Full text]
β2 adrenergic agonist attenuates house dust mite-induced allergic airway inflammation through dendritic cells. BMC Immunol. 15, (2014).[Pubmed, Full text]
